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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52f6dca913f2ecc923186d887209b55ed2f66442464f21b13579a232dda0ab02' 
  AND token = 'wplAqx4nwhnFoWRJNNqcZS7n6kuWclGTooCZoztk7EQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}