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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4464af81220881eb044afe4792e2428d35fd1cff4b31e7efb7e35c0db61942bb' 
  AND token = 'Jkbmb8+kHdDFiBGLPOEpNxhhSrV+PSy3CEYbJmi/a5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}