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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c5b157ebd785f85b5794c3fa887da3095b14f396145b452b0c81de694a66456' 
  AND token = 'HTG4+wGFDC9ZQ958FGJwpoW5s4usLR8RC34vAkpO0kM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}