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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af5b7e783501897dd58515e6e8c6626facd1d4785682b2dc7509c23de28cbdcc' 
  AND token = '/07VAi+VyMPNxgcV0WLN3VKQrgiiSxj+DT7/sSeCJwY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}