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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01cb323f73abe07cc497f2500131f96f5b09e8964ffc151e6b5c00a52990af07' 
  AND token = '4eiijVL9NQT67Pz/llld058Z1RK5YwrLx/IFsMWOhdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}