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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75837e2dd313fea4f3dc39fa5002e7d301d178bcfc27f2de470e32efa305146e' 
  AND token = 'cwi9YHYJtdwWYUx5SGBKRTyT4/W7sSWhGqwzkDMY5/g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00062

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}