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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '162464e7289ddfc661df0a70fa527eac29a3f4581b4f295feae1e431c6612569' 
  AND token = 'e/j19D9UEt6xAvE3pd6yftsrTcaKWMZWkV0CMADJdyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}