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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b431b3fa80816f2c9555471eb6ed6c192ee8fa9b434e0d5939ab22e85dcfd306' 
  AND token = 'OoV7nGm0h6vXhMDOxXBKi3kliV42mOewRLlb9W2kzsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}