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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1af058f0c9b87d6fae26225693192dd9e317b0d0009da558e345069c49516ac' 
  AND token = '/e9SDTPx8UJA+iwBBY9HSg4A8uudSsjVY1dHsBHJSxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}