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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c40994956f4828fb86fdc353792454380f84af3d1e2c5f04c6728aeaddb33188' 
  AND token = '53YTmaEjzxcC6h+myTHD+il5aK1bhce+9pgMV8Nw/4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}