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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5b90b06efda1ddfe240b7c33850a13a360605cb520db2aa17abeb0ac19d5ae4' 
  AND token = 'my/ro8hrHNbWfOwyj2zbdIbJJXN5sB3JwwFKqffpMRQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}