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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d5747dd5ca0e02d46c453a0f9e7f009e7631cb0dccc7597f19372e64ef2a173' 
  AND token = 'tFG54XNIOKHy18flJ30EaIaYGK+46NLniuQMpNJByR0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}