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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a67385617c63b244a0b9082e4ee32ca2f326a1611d6e60110a5577af500cfb7' 
  AND token = 'uAKlUdUhnh1o4wgClvBF88ZR8lM8ZZv5qBBCtiZmmYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}