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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d8a6082537701e50f8e104e9cab6fc9031097e83f73d575d76c5f79b5d1edc' 
  AND token = 'gFgRi9o8HZ+0RS++WimdR6+9xZYu297iH13xJMpid+4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}