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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '597d3b2ad94101db57614bd4e031f145d08058877e1e42b96c528bb5cf4d4426' 
  AND token = 'zneucmmqZHrxTUAWRRd+P5mruwh7WMYv5tgT4flfmQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}