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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce54a47286dc4b0018ba6c2d2d7d162efaaf7b85a32451b40303836f6e303b71' 
  AND token = 'fYIgs3veMS53x6z7fioGD9DLhdKAyX861G/x/6j9TWo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}