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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f54d99f7c321489b62989b4e9f938da128d7f053815754040d8aee364b2c4bd1' 
  AND token = 'tt8SdTvWiVagsf9AtHAYmvQBvuHMNmR5q/WegHHYgiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}