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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c05ab2a5b1521e985c2b16b29508cd2669c25ea6a4fde31aa0739a06edc80e83' 
  AND token = 'NXSX3xApIHmh/UWSi/nwh5GO3dBpWD9f+GIVKzx1+kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}