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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a321f92f721144df4e8fc0c047e994d9d236d8df5df777b01a96d394ac405e3d' 
  AND token = '+uZu/zIM4BbOXeV7O1TfqN5LQwBht+WK71ChTC0f3v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}