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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '410652b905d7a509c4fedf1c90dd2ae3a7568e34cd80781fd6974311906858a2' 
  AND token = 'KLtw//4Nq8Vve18wuBLh2ZIkKvP8suBBeowSULFTNy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}