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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3c6a01650f62947832a825fdf1968a37d98d5e6dd260d8bfd9e29f5d4a7dd70' 
  AND token = 'hO4Tl/L65E2yItbJsVUuWOIUBxqlU0WU3AaJ4cLD7F0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}