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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c467202422be52240d6f477b384752f78bd1b7ff5e3e308150820b87b904eb0' 
  AND token = 'RZw/myM+M88vGn8VyoctcztKXu4F0N2702ia94h27R0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}