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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2df5fbe2487006bf2380152b064b7c87dba5b87478c27be69362a57c582dc148' 
  AND token = '4s+7+XrFvr6d/RHn9geOS/+v7ctkbtgZbyrG2Lo6nsM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}