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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e1d4b0b8d3db26a76af220f936e23d3d88deb19a420dab14ee163e22aa7ac25' 
  AND token = 'X23KEdC+0QfWWMo3fKV2y7KHHONs4UFCP1elFU+KK0I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}