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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18febcb9e47ec33349a0762f615543ca59065c9e3f3f588acacbcfbcf587435a' 
  AND token = 'UwMGE2BT/SPmh6JHfjcm/3jihokJXKTe4PSkUj1ILW4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}