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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ef4b5cc80a0a9231c3868d3d2aafbfb38c03d644556e324e63ce042984e9dbb' 
  AND token = 'tANqIQCzz3F5C5iDjoutCt/oLijO6UpAbRHXnpJ219A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}