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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da3654ca8fc33d1da57e135f019f8ec5a052d9d5e86c5107ad5704fa661254b3' 
  AND token = '18gs3vZcshjK/mS2zxdla6hdFzuvSTommnYxGah0BiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}