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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52b58242170f8612161e8aff3e1abf898d48c14c8ec23283b37abf5b3a3f0e21' 
  AND token = 'jul4vPFYBMljklVOvjk3FxWETPxwguN1Z188i76ZZnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}