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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f185c5f9d3ea72b3b567b67f49ff1563c5de284b8813e5acec56f5d781e21813' 
  AND token = 'YosfWbiTORwJs8RWCAxs9ZOcCc8D5tWRw4++ftbVYIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}