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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '921d8456cf42ce8c6006ae52118e9c50957aef935f0a2070407cfb9df22cf82d' 
  AND token = 'Fsc0Oq50VOjaydCA6/kZWb+h+AhGG/FSVw2WVN8UHzo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}