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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49ac3d20ed4ccf066f7aae9087487247f1e03601ff13e06a33b697b0ebdb57a4' 
  AND token = 'EG/mdC2urZwDBFIF1dHLwenbqR3aB3hODD0M2Oi7i1M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}