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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ebfc6e6f248562ad7a3dba022f258febb5f3e67c41ad92d888d0dc3fcc355b9f' 
  AND token = 'V/VpsQ+oPqJxNkdlP/Np/xAdLDkOpXvcTqU5OQwVMd0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}