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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3107cb85a3f497d917151f58b7a475aad56452e918d7ac3070514c0726568434' 
  AND token = 'SR2Lvts/jN3S6UYRoDPXSw5c9JPDnxfZGN2PA2+aYc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}