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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '761806410f952dd5bb55709f1d7decc0c0685a59a3389345f2f9103edf31fbfd' 
  AND token = 'Tpka9Dz8vqUrKeTkhfnYIQqF2nChwt+MG7aUEDPy2Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}