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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a1180c478acf9f97cd193ece806c187c346dd9d3a2f9cad93c0f6b6efe00c6b' 
  AND token = 't+ELIcR6YgU2jFr3t+A6WZjPG9xZvR6wKVdjGT23ORY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}