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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '375d1783bc5439223d31f5315041111511c7d8dc80ed31cc81e923e112bdf408' 
  AND token = '/853lhoj6Xe2mRFGBiTGIfAd1vQHjg6AM0SZVhKGeu4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}