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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a15c114081bd4f5b2ae07e61f3801cf69dd5ab76b34b986550356e8c3b442c' 
  AND token = 'b6LiIaZ0x8Zays63zxKZF6xsOVOGDelhprpGWlqqL4o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}