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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25a28548fae8fcef2ac7945cd67cbed4f0b13153debeddc4e4ae725027d77a8c' 
  AND token = 'T/WFhdD7p5WLuk6kG4WJ+Y7DBoEAUzVG/u92UcCadp4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}