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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33f9b51779364c78402f50c9ab38fb97e22dd57bf740ef8afa09698b3d9c8300' 
  AND token = '9S0ZSvzk6xQh7Edf7V4s2OnV+Qoap/EXxwQAULd3nsc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}