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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7043aeaa5c82e4293ceb34d06bd7a03366191df927cedb2f168793500c2020a2' 
  AND token = 'Q3E03mshwhbNvtZtpHyyvM42n8dnd81ayQ/C8w4Ss08=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00060

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}