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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b64cdbc6ac79b543d296940959ae0f69e7fcec5cfad286d0500d1419cd1fd5a' 
  AND token = 'uTJQFL+HG5zqmKMPhIIEeNb/QqmzWB4ul9z9diI2+aI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}