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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '484f6a808d697eef8f057be1210ed5c3c1c76ed919ce58fd3441c36c53b9d722' 
  AND token = 'UgpoXzqtmOTibIS+BgWsNpbNwklp/35nXTyN1ZxWwVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}