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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cc61c7b74a12a9d336e6bdbaeb4cea0276de0e2391246dc62b54615446c72571' 
  AND token = 'orEoMw2GHwlE3+9Y68GxaKkY1TJ6mhLC65sTb/E8l24=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}