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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c65b756e90379ec11928c5253e01fd278864cfbeffd9a1fa52c415c22943e44e' 
  AND token = '/iN4s7nEj/SkeDYpPwAL8biKbai65m+EJWask/6IsQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}