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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0072f1aebcb41050e74926f755f80f8e7a94e2f42f88d36d5cd096bc3c2c38b' 
  AND token = 'CZ/rMC0P29+WcQ4PGzzPGYOibx0SmXidXnDm4D0wfqM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}