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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f134b312929c94a8fdd24bf552be1c239e605422e0dda9072d8a54b959188e54' 
  AND token = 'wIxKKBvbXce9lHdi0XvN6VoFYWE9hcS7eHAJh1D7DSk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}