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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e976b13da9dc3cbcd2b24dc4d2389c68e28a8f451f2653f3b0d068db00ee976a' 
  AND token = 'wB/+dFlbg4NB0O6ApEZ1n9mesjeEXATrLsfq49RAvGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}