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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4bde750f976cb55bfa45ff35f0b9bba418d06bb32b56a4f372025b9071b4cc05' 
  AND token = 'ffwfGu3tPvRveRr6SyvhAbZWsTG2WZneTVxfmWUFkiA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}