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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '04b5e3007dfa3b172f3a87236cd5431bd0d9e49f5b6965fdb603d3a6105b0f8e' 
  AND token = 'pw10Q19y2XdB6zGGUgXjeXma5nqzes8y0CWs1xAG0qM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}