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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a4187f5737ff2df18a04d1fecbb72eced6e3298eba24545acc03d919271a411' 
  AND token = '+0XtAGHxLKygHL3Z718v1QujbFpSlNWWnAQx966MH50=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}